一、个人简介

杨立敏，博士，教授，硕士生导师，主要从事功能纳米荧光探针、生物传感器的设计构建与生物应用的研究工作。作为项目负责人，主持承担国家自然科学基金面上项目（2022.01-2025.12）、青年项目（2019.01-2021.12）、山东省精细化学品清洁合成重点实验室和分子与纳米探针教育部重点实验室基金等课题。获2020年度山东省自然科学二等奖（第四位）、2019年度山东省高等学校科学技术一等奖（第三位）、青岛市分析测试协会2021年度科学技术奖一等奖（第五位）各1项。近年来，在Analytical Chemistry、Chemical C32ommunications、ACS Applied Materials & Interfaces等重要学术期刊发表SCI收录论文30余篇。

联系方式：yanglimin@qau.edu.cn  

二、个人科研及教育经历

2019-03-至今        必威    特聘教授、硕士生导师

2018-02至2019-02   必威    讲师

2012-09至2017-12   山东师范大学    分析化学    博士  导师：唐波 教授

2009-09至2012-06   青岛科技大学    分析化学    硕士  导师：李峰 教授

2005-09至2009-06   内蒙古师范大学   化  学     学士

三、代表性论文：

1. Limin Yang, Heng Guo, Ting Hou, and Feng Li*, Uncovering the Interaction Between Intracellular Telomerase Activity and Hydrogen Peroxide During Cancer Cells Apoptosis Utilizing a Dual-Color Fluorescent Nanoprobe, Analytical Chemistry, 2022, 94, 15162-15169.（IF = 8.008）

2. Limin Yang, Xuehan Yin, Bin An, Feng Li*, Precise Capture and Direct Quantification of Tumor Exosomes via Highly Efficient Dual-Aptamer Recognition-Assisted Ratiometric Immobilization-Free Electrochemical Strategy, Analytical Chemistry, 2021, 93, 1709-1716.（IF = 8.008）

3. Limin Yang, Xuehan Yin, Panpan Gai, Feng Li*, Label-free homogeneous electrochemical cytosensor for ultrasensitive detection of cancer cells based on multiaptamer-functionalized DNA tetrahedral nanostructures, Chemical Communications, 2020, 56, 3883-3886.（IF = 6.065）

4. Limin Yang, Bin An, Xuehan Yin, Feng Li*, Competitive coordination-based immobilization-free electrochemical biosensor for highly sensitive detection of arsenic(V) using CeO₂–DNA nanoprobe, Chemical Communications, 2020, 56, 5311-5314.（IF = 6.065）

5. Xuehan Yin, Ting Hou, Bingzheng Huang, Limin Yang*, Feng Li*, Aptamer recognition-trigged label-free homogeneous electrochemical strategy for ultrasensitive cancer-derived exosome assay, Chemical Communications, 2019, 55, 13705-13708. （IF = 6.065）

6. Limin Yang, Bo Liu, Meimei Wang, Jia Li, Wei Pan, Xiaonan Gao, Na Li*, Bo Tang*. A Highly Sensitive Strategy for Fluorescence Imaging of MicroRNA in Living Cells and in Vivo Based on Graphene Oxide-Enhanced Signal Molecules Quenching of Molecular Beacon. ACS Applied Materials & Interfaces, 2018, 10, 6982-6990.（IF = 10.383）

7. Limin Yang, Yuanyuan Chen, Zhengze Yu, Wei Pan, Hongyu Wang, Na Li*, Bo Tang*, Dual-Ratiometric Fluorescent Nanoprobe for Visualizing the Dynamic Process of pH and Superoxide Anion Changes in Autophagy and Apoptosis. ACS Applied Materials & Interfaces, 2017, 9, 27512-27521.（IF = 10.383）

8. Limin Yang, Jia Li, Wei Pan, Hongyu Wang, Na Li*, Bo Tang*, Fluorescence and photoacoustic dual-mode imaging of tumor-related mRNA with a covalent linkage-based DNA nanoprobe. Chemical Communications, 2018, 54, 3656-3659. （IF = 6.065）

9. Limin Yang, Yuanyuan Chen, Wei Pan, Hongyu Wang, Na Li* Bo Tang*. Visualizing the Conversion Process of Alcohol-Induced Fatty Liver to Steatohepatitis in Vivo with a Fluorescent Nanoprobe. Analytical Chemistry, 2017, 89, 6196-6201. （IF = 8.008）

10. Limin Yang, Yanfei Ren, Wei Pan, ZhengzeYu, Lili Tong, Na Li*, Bo Tang*. Fluorescent Nanocomposite for Visualizing Cross-Talk between MicroRNA-21 and Hydrogen Peroxide in Ischemia-Reperfusion Injury in Live Cells and In Vivo. Analytical Chemistry, 2016, 88, 11886-11891.（IF = 8.008）