个人简介：杨立敏，女，1986年6月生，博士研究生/理学博士，教授。

研究方向：功能纳米探针设计合成及应用、生物传感器的设计构建。

学习工作经历：2009年7月毕业于内蒙古师范大学获理学学士学位，2012年7月毕业于青岛科技大学获理学硕士学位，师从李峰，教授2017年12月毕业于山东师范大学获理学博士学位，师从唐波教授。2018年1月起任教于必威并加入泰山学者李峰教授团队。

科学研究：在Analytical Chemistry, ACS Applied Materials & Interfaces, Chemical Communications等重要学术期刊发表发表SCI收录论文30余篇。其中第一作者/通讯作者14篇（影响因子 6.0 以上 12 篇）。

主持及参与课题情况：

国家自然科学基金面上项目2022.01-2025.12

国家自然科学基金青年项目2019.01-2021.12

山东省精细化学品清洁合成重点实验室开放基金

分子与纳米探针教育部重点实验室开放基金

betway必威西汉姆联官网高层次人才启动基金项目2019.03-2024.02

代表性成果列表：

1. Limin Yang, Xuehan Yin, Bin An, Feng Li*, Precise Capture and Direct Quantification of Tumor Exosomes via Highly Efficient Dual-Aptamer Recognition-Assisted Ratiometric Immobilization-Free Electrochemical Strategy, Analytical Chemistry, 2021, 2021, 93, 1709–1716.

2. Limin Yang, Bin An, Xuehan Yin, Feng Li*, A competitive coordination-based immobilization free electrochemical biosensor for highly sensitive detection of arsenic(V) using a CeO2–DNA nanoprobe. Chemical Communications, 2020, 56, 5311–5314.

3. Limin Yang, Xuehan Yin, Panpan Gai, Feng Li*, A label-free homogeneous electrochemical cytosensor for the ultrasensitive detection of cancer cells based on multiaptamer-functionalized DNA tetrahedral nanostructures. Chemical Communications, 2020, 56, 3883–3886.

4. Fangfang Lu#, Limin Yang#, Ting Hou*, Feng Li*, Label-free and “signal-on” homogeneous photoelectrochemical cytosensing strategy for ultrasensitive cancer cell detection, Chemical Communications, 2020, 56, 11126–11129.

5. Xuehan Yin, Ting Hou, Bingzheng Huang, Limin Yang*, Feng Li*, Aptamer recognition-trigged label-free homogeneous electrochemical strategy for an ultrasensitive cancer-derived exosome assay. Chemical Communications, 2019, 55, 13705–13078.

6. Fengjuan Liu#, Limin Yang#, Xuehan Yin, Xiaojuan Liu, Lei Ge*, Feng Li*, A facile homogeneous electrochemical biosensing strategy based on displacement reaction for intracellular and extracellular hydrogen peroxide detection. Biosensors and Bioelectronics, 2019, 141, 111446.

7. Limin Yang, Peng Gao, Yuanlei Huang, Xiao Lu, Qian Chang, Wei Pan, Na Li*, Bo Tang*, Boosting the photodynamic therapy efficiency with a mitochondria-targeted nanophotosensitizer. Chinese Chemical Letters, 2019, 30, 1293–1296.

8. Limin Yang, Bo Liu, Meimei Wang, Jia Li, Wei Pan, Xiaonan Gao, Na Li*, Bo Tang*, A Highly Sensitive Strategy for Fluorescence Imaging of MicroRNA in Living Cells and in Vivo Based on Graphene Oxide-Enhanced Signal Molecules Quenching of Molecular Beacon. ACS Applied Materials & Interfaces, 2018, 10, 6982–6990.

9. Limin Yang, Jia Li, Wei Pan, Hongyu Wang, Na Li*, Bo Tang*, Fluorescence and photoacoustic dual-mode imaging of tumor-related mRNA with a covalent linkage-based DNA nanoprobe. Chemical Communications, 2018, 54, 3656–3659.

10. Limin Yang, Yuanyuan Chen, Wei Pan, Hongyu Wang, Na Li*, Bo Tang*, Visualizing the Conversion Process of Alcohol-Induced Fatty Liver to Steatohepatitis in Vivo with a Fluorescent Nanoprobe. Analytical Chemistry, 2017, 89, 6196–6201.

11. Limin Yang, Yuanyuan Chen, Zhengze Yu, Wei Pan, Hongyu Wang, Na Li*, Bo Tang*, Dual-Ratiometric Fluorescent Nanoprobe for Visualizing the Dynamic Process of pH and Superoxide Anion Changes in Autophagy and Apoptosis. ACS Applied Materials & Interfaces, 2017, 9, 27512–27521.

教学授课情况：

《普通化学I》、《基础化学实验I》、《分析化学III》

获奖情况：

2020 年度山东省自然科学奖，二等奖，排名4/4

2019 年度山东省高等学校科学技术奖，一等奖，排名3/5