鲁莉华（1979.11－）

教授，理学博士，硕士研究生导师

专业：农药残留分析，化学工艺

联系电话：13954297004

电子邮件：lulihua2012@hotmail.com, lulihua2012@qau.edu.cn

地址：山东省青岛市城阳区长城路700号betway必威西汉姆联官网化学楼 517室

工作经历：

2018.09– betway必威西汉姆联官网物理化学教研室 教授

2013.12–2018.09 betway必威西汉姆联官网物理化学教研室 副教授

2007.12–2013.12 必威，物理化学教研室，讲师

2005.07-2007.10 betway必威西汉姆联官网理学院，助教

学习经历：

2012.12–2015.12 香港浸会大学化学系，Dik-Lung Ma课题组攻读博士

2002.09–2005.07 青岛科技大学化工学院 化学工艺，硕士

1998.09–2002.07 青岛科技大学必威，精细化工，本科

鲁莉华教授目前主要从事铱(III)配合物的设计合成及其在生物荧光传感与药物研发上的应用研究工作。目前主持国家自然科学基金青年项目、山东省自然科学基金面上项目、山东省高等学校科技计划项目和青岛市惠民计划项目各1项。在Chem. Sci., Anal. Chem., Chem. Commun., Biosens. Bioelectron., Acs Appl. Mater. Interfaces, Nanoscale等国际知名SCI期刊上发表研究论文50余篇。

部分代表性论文：

（1）X. Li, K. Fan, R. Yang, X. Du, B. Qu, X. Miao*, L. Lu*, A long lifetime ratiometrically luminescent tetracycline nanoprobe based on Ir(III) complex-doped and Eu3+-functionalized silicon nanoparticles, Journal of Hazardous Materials 386 (2020) 121929. (Impact factor: 7.91, JCR一区)

（2）H. Su, M. Zang, L. Lu*, F. Li*, Monitoring matrix metalloproteases based on the selective interaction between an Ir(III) solvent complex and a histidine-rich polypeptide. Chem. Commun., 2019, 55, 7085-7088 (Impact factor: 6.164, JCR一区).

（3）X. Li, K. Fan, W. Kang, R. Yang, B. Qu, L. Lu*,γ-Aminobutyric acid-modified graphene oxide as a highly selective and low-toxic fluorescent nanoprobe for relay recognition of copper(II) and cysteine. Microchim Acta, 2019, 186, 461-469 (Impact factor: 5.479, JCR二区)

（4）L. Lu, H. Su, Q. Liu, F. Li*. Development of a Luminescent Dinuclear Ir(III) Complex for Ultrasensitive Determination of Pesticides. Anal. Chem. 2018, 90, 11716–11722. (Impact factor: 6.042, JCR一区)

（5）L. Lu*, C. Liu, H.-J. Zhong, G. Li, L.-J. Liu, C.-H. Leung*, D.-L. Ma*. Low toxic fluorescent nanoprobe applicable for sensing pH changes in biological environment. Sensor Actuat. B-Chem., 2018, 257, 860–8657. (Impact factor: 5.401, JCR一区)

（6）L. Lu, H. Su, F. Li*, Ultrasensitive Homogeneous Electrochemical Detection of Transcription Factor by Coupled Isothermal Cleavage Reaction and Cycling Amplification Based on Exonuclease III, Anal. Chem., 2017, 89, 8328–8334. (Impact factor: 6.320, JCR一区)

（7）L. Lu, D. S.-H. Chan, D.W.J. Kwong, H.-Z. He*, C.-H. Leung*, D.-L. Ma*. “Detection of nicking endonuclease activity using a G-quadruplex-selective luminescent switch-on probe” Chem. Sci., 2014, 5, 4561–4567. (Impact factor: 9.144, JCR一区)

（8）L. Lu*, Z. Mao, T.-S. Kang, C.-H. Leung*, D.-L. Ma*. A versatile nanomachine for the sensitive detection of platelet-derived growth factor-BB utilizing a G-quadruplex-selective iridium(III) complex. Biosens. Bioelectron., 2016, 85, 300–306. (Impact factor: 7.476, JCR一区)

（9）L. Lu, M. Wang, L.-J. Liu, C.-H. Leung*, D.-L. Ma*. A label-free luminescent switch-on probe for ochratoxin A detection using a G-quadruplex-selective iridium(III) complex. ACS Appl. Mater. Interfaces, 2015, 7, 8313–8320. (Impact factor: 7.145, JCR一区)

（10）L. Lu*, W. Wang, C. Yang, T.-S. Kang, C.-H. Leung*, D.-L. Ma*. Iridium(III) complexes with 1,10-Phenanthroline-based N^N ligands as highly selective luminescent G-quadruplex probes and application for switch-on ribonuclease H detection. J. Mater. Chem. B, 2016, 4, 6791–6796. (Impact factor: 4.872, JCR一区)

（11）L. Lu, M. Wang, L.-J. Liu, C.-Y. Wong, C.-H. Leung*, D.-L. Ma*. A luminescence switch-on probe for terminal deoxynucleotidyl transferase (TdT) activity detection by using an iridium(III)-based i-motif probe. Chem. Commun., 2015, 51, 9953–9959. (Impact factor: 6.567, JCR一区)

（12）L. Lu, W. Wang, M. Wang, T.-S. Kang, J.-J. Lu, X.-P. Chen, Q.-B. Han, C.-H. Leung, D.-L. Ma*. A luminescent G-quadruplex-selective iridium(III) complex for the label-free detection of lysozyme. J. Mater. Chem. B, 2016, 4, 2407–2411. (Impact factor: 4.872, JCR一区)

（13）L.-J. Liu#, L. Lu#, H.-J. Zhong, B. He, D.W.J. Kwong, D.-L. Ma*, C.-H. Leung*. An iridium(III) complex inhibits JMJD2 activities and acts as a potential epigenetic modulator. J. Med. Chem., 2015, 58, 6697–6673. (Co-first author, Impact factor: 5.589, JCR一区)

（14）Z.-Z. Dong#, L. Lu#, C. Yang, S. Li, M.-Y. Lee, C.-H. Leung*, D.-L. Ma*. A MnO2 nanosheet-assisted GSH detection platform using an iridium(III) complex as a switch-on luminescent probe. Nanoscale, 2017, 9(14):4677–4682. (Co-first author, Impact factor: 7.760, JCR一区)