魏红涛,betway必威西汉姆联官网,必威,副教授
教育经历:
2005/03-2009/09,东南大学化学化工学院,博士。
1997/09-2000/06,华中师范大学有机合成研究所,硕士。
1993/09-1997/06,河南师范大学化学系,本科。
工作经历:
1.2010/07-至今,必威。
2.2009/10-2010/06,宁波市微循环与莨菪类药研究所
2.2000/07-2005/03,湖北省农药检定所。
研究方向:
1.功能材料的制备及性能研究。
2.新药与药物载体材料研究。
3.有机中间体合成工艺研究。
主持或参加科研项目(课题)及人才计划项目:
1. 国家自然科学基金青年科学基金项目,51603114,多孔有机网络作为模型结构研究超级电容器电极材料的结构-性能关系,参与。
2. betway必威西汉姆联官网高层次人才启动基金,631309,金催化的氧转移炔烃氧化反应及其在杂环构建中的应用,主持。
3. 山东省中青年科学基金项目,BS2011YY007,基于加成-环合串联反应的杂环化合物新合成方法研究,参与。
4. 山东省自然科学基金项目,ZR011BL003,娑罗子黄酮甙A类似物的合成及抗病毒活性研究,参与。
5. 国家自然科学基金青年科学基金项目,30701052,多巴胺D3受体部分激动剂用于治疗药物成瘾,参与。
研究成果
一、期刊论文 :
(1) Hongtao Wei, Qian Zhang, Yongcai Zhang, Zhanjun Yang, Aiping Zhu, Dionysios D. Dionysiou, Enhancement of the Cr(VI) adsorption and photocatalytic reduction activity of g-C3N4 by hydrothermal treatment in HNO3 aqueous solution, Applied Catalysis A: General, 2015, 521:9-18.
(2) Jin Cai, Hongtao Wei, Kwon Ho Hong, Xiaoqing Wu, Xi Zong, Meng Cao, Peng Wang, Lushen Li, Chunlong Sun, Bo Chen, Gaoxing Zhou, Junqing Chen, Min Ji, Discovery, bioactivity and docking simulation of Vorinostat analogues containing 1,2,4-oxadiazole moiety as potent histone deacetylase inhibitors and antitumor agents, Bioorganic & Medicinal Chemistry, 2015, 23(13): 3457-3471.
(3) Jin Cai, Hongtao Wei, Kwon Ho Hong, Xiaoqing Wu, Meng Cao, Xi Zong, Lushen Li, Chunlong Sun, Junqing Chen, Min Ji, Discovery and preliminary evaluation of 2-aminobenzamide and hydroxamate derivatives containing 1,2,4-oxadiazole moiety as potent histone deacetylase inhibitors, European Journal of Medicinal Chemistry, 2015,96:1-13.
(4) Zhuzhou Shao, Lubin Xu, Liang Wang, Hongtao Wei,Jian Xiao, Catalyst-free tandem Michael addition/decarboxylation of (thio)coumarin-3-carboxylic acids with indoles: facile synthesis of indole-3-substituted 3,4-dihydro(thio)coumarins, Organic & Biomolecular Chemistry, 2014,12:2185-2188.
(5) Jian Xiao, Yuye Chen, Shuai Zhu, Liang Wang, Lubin Xu, Hongtao Wei, Diversified Construction of Chromeno[3,4-c]pyridin-5-one and Benzo[c]chromen-6-one Derivatives by Domino Reaction of 4-Alkynyl-2-oxo-2H-chromene-3-carbaldehydes, Advanced Synthesis & Catalysis,2014,356(8):1835–1845.
(6) Hongtao Wei, Min Sun, Min Ji, A straightforward expeditious synthesis of 5-nitrobenzo[b]thiophene-2-carbaldehyde, Journal of chemical research, 2009, (6):359-360.
(7) Min Sun, Youguang Zheng, Hongtao Wei, Junqing Chen, Min Ji, QSAR studies on 4-anilino-3-quinolinecarbonitriles as Src kinase inhibitors using robust PCA and both linear and nonlinear models, Journal of Enzyme Inhibition and Medicinal Chemistry, 2009, 24(5): 1109-1116.
(8) M in Sun, Junqing Chen, Hongtao Wei, Shuangqing Yin, Yan Yang, Min Ji, QSAR and Classification Analysis of Diaryl Ureas against VEGFR-2 Kinase Using Linear and Nonlinear Models, Chemical Biology & Drug Design,2009,73(6):644–654.
(9) Min Sun, Youguang Zheng, Hongtao Wei, Junqing Chen, Jin Cai, Min Ji, Enhanced Replacement Method-based Quantitative Structure–Activity Relationship Modeling and Support Vector Machine Classification of 4-Anilino-3-quinolinecarbonitriles as Src Kinase Inhibitors, QSAR & Combinatorial Science,2009,28(3):312–324.
(10) Min Sun, Hong-Tao Wei, Dong Li, You-Guang Zheng, Jin Cai,Min Ji, Mild and Efficient One-Pot Synthesis of 2-Imidazolines from Nitriles Using Sodium Hydrosulfide as Catalyst, Synthetic Communications,2008,38(18):3151-3158.
(11) Hongtao Wei, Jin Cai, Min Sun, Min Ji, Synthesis of Substituted Thieno [2,3-b] pyrroles, Heteroatom Chemistry,2007,18(3):236–238.
(12) Hong-Tao Wei,Min Ji,The ethyl tetraester of ranelic acid,Acta Crystallographica Section E,2007,63:o1341-o1343.
二、授权发明专利
(1)曲宝涵,魏红涛,刘晓杰,郝智慧,(2S,3R)-1-取代苄基-2-烯丙基-3-羟基哌啶及其制备方法, 2015.04.15,中国,CN103204799B.
(2)吉民,魏红涛,吴晓晴,用作组蛋白去乙酰酶抑制剂的异羟肟酸类化合物及其用途,2012.12.26,中国,CN101648923B.
(3)吉民,魏红涛,吴晓晴,组蛋白去乙酰酶抑制剂异羟肟酸类化合物及其用途,2012.08.15,中国,CN101648924B.
(4)吉民,魏红涛,吴晓晴,用作组蛋白去乙酰化酶抑制剂的异羟肟酸类化合物及其用途,2012.08.15,中国,CN101648940B.
(5)吉民,魏红涛,吴晓晴,用作组蛋白去乙酰酶抑制剂的三氟甲基酮类化合物及其用途,2012.02.08,中国,CN101648920B.
(6)吉民,魏红涛,吴晓晴,用作组蛋白去乙酰化酶抑制剂的苯甲酰胺化合物及其用途,2011.11.02,中国,CN101648921B.
(7)吉民,魏红涛,吴晓晴,苯甲酰胺类组蛋白去乙酰酶抑制剂及其用途,2011.08.31,中国,CN101648922B.